Selected work

Portfolio

One flagship project that defines my profile — documented end to end — and the student startup where the maker mindset began.

01 — Flagship

Pneumoscope — an AI-powered connected diagnostic device

The Pneumoscope is a connected diagnostic device — a smart, digital stethoscope — designed to capture several physiological signals at once (digital lung auscultation, pulse oximetry and contact thermometry) and to surface AI-assisted detection of respiratory pathology at the point of care.

As Head of R&D at Geneva University Hospitals (HUG), I owned the device end to end: from the original patented design through electronics, miniaturization and a 3D-printed enclosure, to a CE-mark compliant Class IIa medical device produced at industrial scale.

2019 – 2025 EU MDR · Class IIa CE European patent (granted 2025) Nature Digital Medicine Clinical across 5 countries 1.5M CHF funding
Alexandre J.E Perez holding the final, plastic-injected Pneumoscope
The Pneumoscope — first plastic-injected unit, in hand

That's me, building a Pneumoscope by hand — from the first component to a finished, CE-mark compliant device. I take hardware all the way.

↳ Retrospective

From concept to industrialization — 29 steps, 2019 → 2025

Every stage of the journey, exactly as it happened — design, electronics, prototypes, clinical trials, regulatory testing and industrial production.

Pneumoscope development — a retrospective from 2019 to 2025: POC (V1), MVP (V2) and final Product (V3)
V1 · 2019 – 2021

Proof of concept

Proving the idea: from the patented concept to a working 3-in-1 prototype and a first companion app.

Original design (patented)
Mar – Jun 2019 · 4 months

Original design (patented)

Designing the device and defining a method for the simultaneous measurement of a patient's parameters — the basis of the European patent filing.

Electronics PoC (audio + oximeter)
Jul – Sep 2019 · 3 months

Electronics PoC (audio + oximeter)

Rapid prototyping to benchmark existing electronic-stethoscope and pulse-oximeter solutions.

First functional prototype (one sensor)
Oct – Nov 2019 · 2 months

First functional prototype (one sensor)

Miniaturizing the electronics to embed them in a compact, portable case.

Testing case finishing
Dec 2019 · 1 month

Testing case finishing

Testing different techniques and methods for the 3D-printing finishing of the housing.

Second prototype (2 sensors)
Jan – Dec 2020 · 12 months

Second prototype (2 sensors)

Optimizing the electronic design to include a transmission pulse oximeter, with hepia's electronics & optoelectronics labs.

Designing acoustic characteristics
Jan – Jun 2021 · 6 months

Designing acoustic characteristics

Optimizing and characterizing the acoustic signal, with hepia's acoustics & electronics labs.

Optimization & adding a 3rd sensor
Jun – Sep 2021 · 4 months

Optimization & adding a 3rd sensor

Optimizing the electronics and adding the contact thermometer, with hepia's electronics lab.

3rd prototype (3-in-1)
Sep – Dec 2021 · 4 months

3rd prototype (3-in-1)

Validating the technical feasibility of a 3-in-1 device: digital stethoscope, contact thermometer and pulse oximeter.

First App (PoC)
Jan 2020 – Dec 2021 · 2 years

First App (PoC)

A proof-of-concept app communicating over BLE with the Pneumoscope, plus a mock-up of the final app design tested with end-users.

V2 · 2022 – 2024

MVP

An industrial-grade redesign with end-users, a clinical-grade prototype and a first clinical trial.

Designing the Pneumoscope MVP
Jan 2022 – Mar 2023 · 14 months

Designing the Pneumoscope MVP

Designing a tool that meets user and technical requirements, based on the patented design. (with BUREAU 141)

Co-development with end-users
Jan 2022 – Dec 2023 · 2 years

Co-development with end-users

Interviews, rapid prototyping and user tests to validate design, ergonomics and functions with doctors, nurses and pharmacists. (with BUREAU 141)

Audio optimization (2nd iteration)
Aug – Oct 2022 · 3 months

Audio optimization (2nd iteration)

Optimizing the acoustic signal against the specs of 3M™ Littmann® CORE & 3200 digital stethoscopes.

Industrialization of the electronics
Nov 2022 – Dec 2023 · 13 months

Industrialization of the electronics

A complete redesign of the electronics to meet industrial and regulatory standards.

Electronics implementation
Jan – Apr 2023 · 4 months

Electronics implementation

Redesigning the inside of the case to fit the new electronic board.

Photo shooting
May – Jun 2023 · 2 months

Photo shooting

Producing communication material for product and business development. (with BUREAU 141)

Product pre-testing (CT & CE)
Jun – Dec 2023 · 6 months

Product pre-testing (CT & CE)

Pre-testing prototypes in lab with EMC and electrical-safety tests to meet medical standards.

First medical-compliant prototype
Jan – Apr 2024 · 4 months

First medical-compliant prototype

Producing prototypes for the first Pneumoscope clinical trial to validate hardware performance.

Second App (MVP)
Jun 2023 – Apr 2024 · 10 months

Second App (MVP)

Updating the app to include the DeepBreath AI model and an offline mode for clinical studies.

Clinical trial #1 — HUG, Geneva
May – Aug 2024 · 4 months

Clinical trial #1 — HUG, Geneva

Setting up Pneumoscope packs for the clinical study at Geneva University Hospital on 250 patients.

Results of clinical trial #1
2024 · Results

Results of clinical trial #1

Two senior doctors blindly rated the quality of 100 recorded lung sounds. The Pneumoscope was preferred over the 3M™ Littmann® CORE, and the AI model reached a strong AUC.

64% preferred vs Littmann COREAI · 0.89 AUC
V3 · 2024 – 2025

Product

Industrialization: plastic injection, CE testing, a granted patent and clinical trials across Africa.

Housing industrialization
Apr – Jun 2024 · 3 months

Housing industrialization

Optimizing the housing design for plastic injection and assembly.

Pneumoscope housing elements
Jul – Oct 2024 · 4 months

Pneumoscope housing elements

Designing and rapid-prototyping housing elements to facilitate production and final assembly.

Plastic injected part (FOT)
Nov – Dec 2024 · 2 months

Plastic injected part (FOT)

First-Out-of-Tool plastic-injected part, in biocompatible material.

App beta version (Product)
Sep 2024 – Mar 2025 · 7 months

App beta version (Product)

The final app for the B2B segment (design freeze for CE), meeting user and medical requirements.

Clinical study in Congo — setup
Jan – Feb 2025 · 2 months

Clinical study in Congo — setup

Producing and setting up 8 full Pneumoscope packs for the clinical study in the DRC.

European patent — granted
29 January 2025

European patent — granted

The European patent protecting the design and method behind the Pneumoscope was granted.

WO2022253723A127 countries
Clinical studies in Africa
May – Dec 2025 · 7 months

Clinical studies in Africa

Producing and setting up 17 Pneumoscope study packs and training doctors to prepare clinical trials in 4 African countries (Ethiopia, Mozambique, Gabon, Congo).

Product testing for CE marking
Jun – Dec 2025 · 6 months

Product testing for CE marking

Testing the device in an accredited lab (Eurofins) for CE marking: EMC/radio, biocompatibility and electrical safety.

Product industrialization
Mar – Dec 2025 · 10 months

Product industrialization

Producing the first industrialized batch (100 units) with industrial partners.

02 — Origin

3Dfunlab — where the maker mindset began

While still a microsystems-engineering student, I co-founded 3Dfunlab, a Geneva 3D-printing and rapid-prototyping startup. The mission was to make 3D printing genuinely accessible — and to do it responsibly, with a strong social and environmental focus.

It was my first taste of taking a hardware idea all the way: building the machines, printing for clients, and selling B2B. The venture drew coverage in the Geneva and Swiss business press, was featured live, in prime time, on Swiss national television (RTS — T.T.C.), and was presented at an international youth-entrepreneurship event at the Palais des Nations.

3Dfunlab is secondary to the Pneumoscope — but it's the origin of the builder-and-entrepreneur instinct that defines how I work today.

Co-founder & CTO 2012 – 2016 Hardware & 3D printing Geneva Live prime-time TV · RTS
Alexandre J.E Perez on the live RTS T.T.C. ‘Spéciale innovation’ set, demoing the 3Dfunlab 3D printer with host Patrick Fischer
▶ Watch on RTS — T.T.C. “Spéciale innovation” (live, prime time)
RTS · T.T.C. (Toutes Taxes Comprises) — I appeared live, in prime time on this national-TV “Spéciale innovation” show to demo 3Dfunlab's 3D printer. UNCTAD Global Entrepreneurship Programme 2013 — Palais des Nations, Geneva United Nations · UNCTAD — Global Entrepreneurship Programme, Geneva 2013.